Generic Semaglutide: Lower-Cost Semaglutide is Here!
BUY NOW
We Ship To The U.S. Only
Farxiga vs Jardiance: In-Depth Comparison
- Posted On:
- 18 Jun, 2026
- 12 min read
-
Farxiga (Dapagliflozin Propanediol Monohydrate)
Farxiga (Dapagliflozin Propanediol Monohydrate) is an oral medication that helps lower blood sugar in adults with type 2 diabetes by blocking the reabsorption of glucose in the kidneys.Starting From $120.00 -
Jardiance (Empagliflozin): A once-daily pill that helps lower blood sugar levels in adults with type 2 diabetes.Starting From $109.00
10% Off On Your First Order
Click on the Copy Code button to copy your code.
No Expiry
Exclusive On Duty Free Meds Only
Farxiga and Jardiance are two name-brand SGLT2 inhibitor medications used to help with issues such as type 2 diabetes, heart failure, and protection of the kidneys. This article will help readers understand how these two medications compare in areas like effectiveness and dosing. It will also compare other areas like safety and cost.
- Jardiance (Empagliflozin): A once-daily pill that helps lower blood sugar levels in adults with type 2 diabetes.Starting From $109.00
-
Farxiga (Dapagliflozin Propanediol Monohydrate)
Farxiga (Dapagliflozin Propanediol Monohydrate) is an oral medication that helps lower blood sugar in adults with type 2 diabetes by blocking the reabsorption of glucose in the kidneys.Starting From $120.00
10% Off On Your First Order
Click on the Copy Code button to copy your code.
No Expiry
Exclusive On Duty Free Meds Only
- Farxiga and Jardiance are both SGLT2 inhibitors with very similar overall benefits
- Both are taken orally in daily doses
- Farxiga and Jardiance both help lower A1C and reduce heart-failure hospitalizations
- Both medications are used to help patients with type 2 diabetes, heart failure, and kidney protection
- Cost and insurance coverage often help patients make the final choice between the medications since clinical effectiveness is similar
Farxiga vs. Jardiance: Key Drug Facts Compared
| Feature | Farxiga | Jardiance |
| Generic Name | Dapagliflozin | Empagliflozin |
| Drug Class | SGLT2 Inhibitor | SGLT2 Inhibitor |
| FDA-Approved Uses |
|
|
| Dosing Frequency | Once daily | Once daily |
| Impact on A1C |
|
|
| Weight-Loss Effects |
|
|
| Heart/Kidney Protection |
|
|
| Common Side Effects |
| UTIs, yeast infections |
| Price (USA) | $600/month | $630/month |
| Price (Canada) | $120+ | $109+ |
What Is Farxiga?
Farxiga is an SGLT2 inhibitor medication that is used for treating conditions like type 2 diabetes and heart failure – both HFrEF and HFpEF. It also helps delay the progression of chronic kidney disease. This medication works by lowering pressure on the kidneys and reducing the kidneys’ glucose absorption.
Findings from Trials
Results from the DECLARE-TIMI 58 trial show that dapagliflozin lowers insulin resistance and cuts major heart risks. The drug also helps prevent heart failure and slows kidney decline in most people with diabetes. The DAPA-HF trial was also conducted on this medication. This trial showed that this treatment lowered the combined risk of heart failure events or cardiovascular death and produced a 5% absolute reduction over 18 months. It also showed that the medication was effective for improving survival rates and kidney health. The DAPA-CKD trial showed that this medication lowered the risk of the main kidney and heart outcome in both groups – with or without diabetes. The drug also showed steady benefits across all secondary outcomes. This included kidney-specific events, heart failure events, and overall survival. The response was similar across different causes of kidney disease.
What Is Jardiance?
Jardiance is another SGLT2 inhibitor that has been approved for type 2 diabetes and heart failure – as well as chronic kidney disease. This medication uses the same SGLT2 pathway as Farxiga.
Findings from Trials
The EMPA-REG OUTCOME trial showed that empagliflozin drastically reduced cardiovascular events in patients with type 2 diabetes and established cardiovascular disease. It led to a 14% reduction in major adverse cardiovascular events – which was driven by a 38% reduction in cardiovascular death and a 35% reduction in heart failure hospitalizations. The EMPEROR-Reduced trial added strong support for using SGLT2 inhibitors in heart failure. Empagliflozin became the second drug in this class – after dapagliflozin – to show meaningful reductions in cardiovascular death and hospitalizations for heart failure in people with severe disease (both with and without diabetes). The EMPEROR-Preserved trial further showed that this medication lowered the risk of cardiovascular death or hospitalizations for heart failure in patients with preserved ejection fraction.
Shared Uses of Farxiga and Jardiance
Both of these medications share common uses such as being used to lower blood sugar for type 2 diabetes patients. They also support modest weight loss and help lower blood pressure. Both medications can be useful for the prevention of hospitalizations due to heart failure. They also have kidney-protecting benefits. Patients taking these medications are prescribed them orally and to be taken once per day.
Key Differences Between Jardiance vs. Farxiga
Approved Uses
Both medications are approved for use in treating type 2 diabetes and related cardiovascular risk. They are also approved for helping patients fight against heart failure and chronic kidney disease. The differences for their use are that Farxiga specifically includes urgent heart failure visits. Farxiga also targets heart failure hospitalization and Jardiance targets cardiovascular death specifically.
Effectiveness
Farxiga and Jardiance work similarly to lower A1C levels. They also have similar effectiveness in many of their main uses. Jardiance may have a little more cardioprotective evidence in some studies compared to Farxiga. However, Farxiga may have more broad kidney disease evidence.
Dosing
Both medications are made for daily dosing. However, dosing strength is a little different. Patients taking Farxiga are usually started on 5 mg doses per day. This dose is sometimes raised to 10 mg per day if additional treatment is needed. Jardiance patients are usually started on a 10 mg dose. This dose can then be raised to 25 mg per day if additional treatment is needed.
Side Effects
Farxiga and Jardiance both have some shared side effects like genital infections and UTIs. These medications may cause dehydration in some patients. The most frequently reported side effects of Jardiance are urinary tract infections and genital yeast infections–-particularly in women. The most common side effects for Farxiga include yeast infections for both male and female genitals. The most common side effects for this medication also include increased urgency for urination.
Special Populations
Farxiga (dapagliflozin) is approved in the U.S. to help reduce the risk of sustained declines in estimated glomerular filtration rate (eGFR) and the development of end-stage kidney disease in adults with chronic kidney disease. It also lowers the risk of cardiovascular death and hospitalizations for heart failure. Jardiance is more commonly used for patients with cardiovascular disease.
Safety and Warnings
Farxiga and Jardiance can lead to diabetic ketoacidosis – especially for patients with type 1 diabetes mellitus and other ketoacidosis. However, this rarely occurs. Side effects like genital yeast infections are much more common. Patients taking these medications may also experience issues like volume depletion and genitourinary infections. Some patients taking this medication may also develop issues such as hypoglycemia or hypersensitivity reactions. Lower-limb amputations have been reported in certain patients with chronic kidney disease using Jardiance.
Allergic reactions to these medications may be indicated by symptoms like rash, hives, or swelling of the face. These symptoms are a sign of an emergency and patients experiencing these symptoms should seek immediate medical attention. It is important for patients to stay hydrated while taking these medications and to evaluate kidney function before and during treatment to minimize these risks.
Comparing Cost and Insurance Coverage
Farxiga has a list price of about $600 per month and the list price for Jardiance is about $630 per month. The prices are around these amounts without insurance. Farxiga is the only one of the two that has a lower-cost generic version. Insurance covers both medications similarly. They are covered under most commercial and government insurance plans.
Some patients may also be able to use savings programs offered by the medication’s manufacturer to save money. Jardiance has a savings program that allows patients to spend as little as $10 per month in some cases. Some Farxiga patients may be able to get their monthly prescription fully covered with these programs.
Patients without coverage may be able to save more from when ordering Farxiga or Jardiance from Canada at Duty Free Meds. Patients may be able to save up to 80% off their medications with Canadian pricing.
Comparison of Farxiga and Jardiance Dosages
| Use | Farxiga | Jardiance |
| Type 2 Diabetes |
|
|
| Heart Failure | 10 mg once per day | 10 mg once per day |
| Chronic Kidney Disease | 10 mg once per day | 10 mg once per day |
Is Jardiance or Farxiga The Right Choice For You?
Whether Jardiance or Farxiga is the choice depends on factors such as the personal goals of the patients – such as goals for blood sugar levels or heart/kidney priorities – -and comorbidities – such as heart failure or chronic kidney disease. Patients may also choose one medication over the other based on how much insurance coverage they are able to get for the medication.
Healthcare professionals may also recommend one medication over the other to patients based on how they tolerate the medications and their side-effect history. However, many patients do equally well on either of these medications. The final decision should be made with the input of a professional healthcare provider.
What to Know When Switching Between Farxiga and Jardiance
It is possible to switch within the SGLT2 class if one medication is not being tolerated. However, it is not likely that most patients will notice much of a difference when switching between Farxiga and Jardiance. Both of these medications come with similar strength options. This makes the dosing adjustments when switching from one to another more straightforward than they would be when switching between many other medications. Switching between these medications requires guidance from a physician. This way, patients can avoid unwanted effects such as glycemic instability or dehydration. It is also important that patients keep monitoring their kidney function and hydration after they make the switch.
Healthcare professionals may also recommend one medication over the other to patients based on how they tolerate the medications and their side-effect history. However, many patients do equally well on either of these medications. The final decision should be made with the input of a professional healthcare provider.
FAQs
Is Farxiga more effective than Jardiance for weight loss?
Neither medication is meant for weight loss. However, they do cause similar weight loss effects. Studies show patients may lose up to about 7lbs on Farxiga and about 2.5% to 2.8% of their body weight on Jardiance.
Is Farxiga or Jardiance safer for heart failure?
Both are very safe and well-studied for heart failure. Farxiga has strong evidence across both HFrEF and HFpEF and reduces hospitalizations and urgent HF visits. Jardiance shows especially strong protection against cardiovascular death and HF hospitalizations.
Can you take Farxiga or Jardiance with metformin or GLP-1 drugs?
These medications may be taken either alone or alongside the use of metformin or GLP-1 drugs.
What happens if you stop one and switch to another?
Most people do not notice a major difference because the medications work very similarly. These switches should still never be made without the guidance of a healthcare professional.
Are Farxiga or Jardiance used for prediabetes?
No. Neither drug is FDA-approved for prediabetes.
What is more expensive, Farxiga or Jardiance?
Prices of the two medications are similar in the U.S. However, Jardiance may be a little more expensive without insurance (with a list price of about $630 per month versus Farxiga’s list price of about $600 per month).
Can you use Farxiga and Jardiance at the same time?
No. These medications work the same way. Combining them adds no benefits and increases the risk of dehydration and harmful side effects.
The Bottom Line
Both Farxiga and Jardiance are well-studied SGLT2 inhibitors that have overlapping benefits for patients. They have both been proven to be effective treatment options for many patients. The main differences between these medications come down to factors like kidney disease approval and cardiovascular evidence. It also may come down to factors like dosing ranges and insurance coverage. Patients should review their health goals and conditions with their provider to determine the best fit for them.
Visit Duty Free Meds today to purchase affordable prescription medication online, including Farxiga and Jardiance.
Sources
Disclaimer: The information presented here is intended solely for educational purposes and should not be interpreted as medical advice, a diagnosis, or specific treatment recommendations. It does not imply endorsement of any particular medication or therapy. Health conditions and treatment responses can differ significantly between individuals; thus, this information is not a guarantee of safety, suitability, or effectiveness for anyone in particular. Always seek the guidance of a healthcare professional for personalized medical advice and consult them before making any health or treatment decisions.
