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Is There a Generic for Eliquis?​

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Eliquis (apixaban) is an oral blood thinner that is prescribed to help lower the risk of stroke for patients with AFib. It is also used to reduce the risk of blood clots for patients with deep vein thrombosis or pulmonary embolism and for those who have recently had hip or knee replacement procedures. Many patients wonder if a cheaper version of this medication exists since it can often be very expensive without coverage. This article will cover whether a generic version of this medication exists – or when it may be – and what other alternatives exist.

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Key Takeaways
Key Takeaways

Is There a Generic for Eliquis?

Generic apixaban has already been approved and will be a cheaper alternative to the name-brand medication. However, the availability of this medication is dependent on region and manufacturer agreements. Generic Eliquis is available in Canada and several other international markets. It is still not sold in U.S. retail pharmacies – and likely will not be until at least April 2028 – because of existing patent protection. Supply and pharmacy availability may still be limited in some areas even if generic approval exists.

When Did the Generic for Eliquis Become Available?

The manufacturer of the medication says it expects that the generic version will start making its way into retail pharmacy stores in the U.S. at the beginning of April 2028. However, the expiration of the patents in the EU is expected to happen as early as the second half of 2026 – meaning it could be sold there even sooner.

The first two brands approved to make generic apixaban were Micro Labs Limited and Mylan Pharmaceuticals Inc. back in 2019. Teva also tried to launch a generic version of the medication. However, they are currently unable to do so because of an ongoing patent dispute.

The switch from brand-name Eliquis to generic apixaban in U.S. retail pharmacies is still on hold since patent extensions and ongoing legal disputes are expected to delay availability until between 2026 and 2028. Some pharmacies may still carry only the brand name for a period after generics are approved to be sold because production may still need to be ramped up and the medication may not become immediately available. Existing name-brand inventory will also still need to be sold and some patients may still prefer the name-brand version.

Understanding the Difference Between Brand-Name and Generic Eliquis (Apixaban)

 EliquisApixaban
Active IngredientApixabanApixaban
Efficacy and Safety
  • Comparable efficacy and safety in preventing:
    • Risk of stroke and blood clots in patients with non-valvular AFib
    • Blood clots in the veins of the legs after hip or knee replacement surgery
    • Recurrent DVT or PE after initial clot treatment
  • This medication is also proven to be safe and effective for the treatment of existing DVT and PE
Same therapeutic effect and safety as Eliquis (generics must meet strict bioequivalence standards)
Inactive Ingredients

Inactive ingredients:

  • Anhydrous lactose
  • Croscarmellose sodium
  • Magnesium stearate
  • Microcrystalline cellulose
  • Sodium lauryl sulfate

Film coating contains:

  • Hypromellose
  • Lactose monohydrate
  • Titanium dioxide
  • Triacetin
  • Yellow iron oxide (in the 2.5 mg tablets)
  • Red iron oxide (in the 5 mg tablets)
Ingredients (like colors and fillers) may vary by manufacturer
Cost U.S. (Without Insurance)About $809 per month (with a $606 per month list price)N/A
Cost U.S. (With Insurance)
  • Average of $38 per month with commercial insurance
  • Average of $54 per month with Medicare
N/A
Cost in Canada$159+ per month$159+ per month
AvailabilityAvailable in the U.S., Canada, and internationally
  • Generic available in Canada and some international markets
  • Not yet available in the U.S.

How to Get Generic Eliquis

There are a few different ways that patients may be able to get generic Eliquis. These ways might include asking their doctor when/if their prescription can be filled with apixaban. They could also try checking availability at local pharmacies. Different locations may get their stock in at different times.

Patients who are purchasing this medication should make sure to compare prices between pharmacies to find the best rate. They should also make sure to verify their insurance coverage. Many plans may now cover generic apixaban instead of brand-name Eliquis. Patients without coverage may be able to use their prescription to order from licensed mail-order or Canadian pharmacies for additional savings.

This medication should never be purchased from non-reputable sources. Patients should verify the legitimacy of the pharmacy before buying the medication to make sure it is high-quality and safe to use. They can buy Eliquis for cheaper Canadian prices from prescription fulfillment services like Duty Free Meds. Patients can order this medication and have it shipped directly to their homes after adding their dosage to the cart and uploading their prescription at checkout.

Why Generic Eliquis May Still Be Hard to Find

Patent protections held by Bristol Myers Squibb and Pfizer continue to prevent generic apixaban from entering the U.S. market. Generic Eliquis is not expected to become available in U.S. retail pharmacies until at least April 2028 as a result. Generic manufacturers may require time to scale production and establish supply chains after this to fulfill regulatory and distribution requirements after approval. This may cause the medication to take a little longer to reach the market after the patents expire. Another factor that can contribute to delays is that insurers and pharmacies may also still prioritize brand-name stock until their contracts expire.

Alternatives if Generic Eliquis Isn’t Available

Patients may have some different options for alternative medications that are more convenient to purchase. This includes other direct oral anticoagulants like:

  • Xarelto (rivaroxaban)
    This medication has similar uses to Eliquis. However, it also has some additional uses – such as for minimizing the risk of cardiovascular issues in people with coronary artery disease or lowering the clotting risk for patients with peripheral artery disease. This anticoagulant may come with a slightly larger bleeding risk compared to Eliquis. This medication can often be found for about $821 per month without insurance – making it a more expensive option in many cases.
  • Pradaxa (dabigatran)
    This medication also has similar uses to Eliquis. The main difference between the two is that Pradaxa contains the direct thrombin inhibitor dabigatran. This causes the medication to work by blocking the thrombin clotting factor in order to stop blood clot formation. This medication is also often a cheaper option at about $568 per month without insurance.
  • Savaysa (edoxaban)
    This may be a good alternative solution for AFib patients. This is another factor Xa inhibitor. One of the biggest differences between the medications is that this one is usually only taken once per day instead of twice per day. This is another medication that is often a cheaper option – costing around $530 per month without insurance. This medication is not advised for patients with liver impairment.

The most traditional alternative to Eliquis is Warfarin. This medication is a vitamin K antagonist instead of an oral anticoagulant. It acts by interfering with the liver’s ability to use vitamin K in forming clotting factors. There are more generic versions of this medication readily available. This is why it is often the cheapest option – often only $23 per month without insurance. The dose of this medication will be dependent on International Normalized Ratio (or INR) values obtained through regular blood test monitoring.

Cost and Savings Considerations

The FDA estimates that generic medications can often be as much as 80% to 85% less than their name-brand counterparts. This can be a great way for patients to save on their medication when it becomes available. Another way to save is to look for the manufacturer’s coupons and patient assistance programs for Eliquis. Eligible commercially insured patients can use the Eliquis Co-pay Card to pay as little as $10 for their first 30-day or 90-day supply. Subsequent 90-day refills may cost as little as $30. This benefit lasts for up to 24 months with a maximum annual savings of $6,400.

The patient assistance program offered by the manufacturer may also help some patients get full coverage for the medication if they are residents of the U.S. or one of its territories without insurance coverage. Their annual household income must also be $46,950 or less – or $63,450 or less for a two-person household. Other requirements may also apply.

Patients can also save on their medication when they buy Eliquis from a licensed international pharmacy or prescription fulfillment service in Canada. For example, Duty Free Meds can help patients save up to 80% on their prescription medications.

The Bottom Line

Generic Eliquis – also known as apixaban – has been approved. However, it still may not be widely stocked everywhere. Both brand and generic versions offer the same medical benefits. Patients should speak with their pharmacist or doctor about cost-saving options and safe alternatives.

Visit Duty Free Meds to purchase affordable medication online, including name and generic Eliquis.

FAQs

Sources
Casey, A., & Muldownwey, L. Kirsty. (2023, December 15). Supreme Court Refuses Teva Leave to Appeal Preliminary Injunction Order. WILLIAM FRY https://www.williamfry.com/knowledge/supreme-court-refuses-teva-leave-to-appeal-preliminary-injunction-order/
Rx ELIQUIS® (apixaban) Home Page. (n.d.). ELIQUIS® https://www.eliquis.bmscustomerconnect.com/
SAVINGS AND FREE TRIAL OFFER RESOURCES. (n.d.). ELIQUIS® https://www.eliquis.bmscustomerconnect.com/savings

Disclaimer: The information presented here is intended solely for educational purposes and should not be interpreted as medical advice, a diagnosis, or specific treatment recommendations. It does not imply endorsement of any particular medication or therapy. Health conditions and treatment responses can differ significantly between individuals; thus, this information is not a guarantee of safety, suitability, or effectiveness for anyone in particular. Always seek the guidance of a healthcare professional for personalized medical advice and consult them before making any health or treatment decisions.

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