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Humalog Sliding Scale

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(Pharm D), MBA, M.Phil and MSPH

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Humalog (insulin lispro) is one of the brands of insulin that patients struggling with type 1 or type 2 diabetes use to help control their blood sugar levels. This type of insulin is considered to be a mealtime insulin and it may be used alongside other basal insulins. A “sliding scale” is a term that is commonly discussed when it comes to diabetes care. This term refers to a method for adjusting the amount of insulin based on the person’s blood sugar level at the time it is to be given. The purpose of this article is to explain what a Humalog sliding scale is, as well as how it is used and other important considerations.

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Key Takeaways

Humalog Sliding Scale Sample

Blood Sugar Level Administration Amount (in Units)
Under 70 0 (start hypoglycemia protocol)
Between 70 and 150 0
Between 151 and 174 2
Between 175 and 199 4
Between 200 and 224 6
Between 225 and 249 8
Between 250 and 274 10
Between 275 and 299 12
Above 300 14 (and call healthcare provider)
Humalog Sliding Scale
Humalog Sliding Scale
Note: charts are not universal and should be adjusted per patient. Hypoglycemia protocol includes more than simply ceasing to take more insulin. This protocol may also include consuming 15-20 g of fast-acting carbohydrates and rechecking blood sugar levels every 15 minutes after this treatment is given. This process may be repeated until blood sugar levels rise above 70 mg/dL. Severe hyperglycemia may need to take a glucagon injection or intravenous glucose.

What Is Meant by Sliding Scale Insulin Dosing?

The sliding scale is an insulin dose scale that gets adjusted based on the patient’s current blood glucose reading. This scale is used for short and rapid-acting insulin doses and coincides with a pre-determined chart. This type of therapy method is different from fixed-dose therapy – where the patients take the same insulin dose before their meals each day with just intermittent dosing changes instructed by the prescriber being done on occasion (if necessary).

Basal-bolus regimens are like sliding scale regimens in that both of these methods are used to help with the management of hyperglycemia in patients. However, sliding scales are reactive and correction-based only. Basal-bolus treatment consists of a daily long-acting insulin in combination with a rapid-acting insulin that is used around the patient’s meal times for correcting hyperglycemia and covering carbohydrate intake. It is meant to mimic physiologic insulin responses for patients too. This treatment is usually more favorable for use by doctors compared to sliding scale methods – especially for long term use since it better mimics natural insulin secretion.

Sliding scales for insulin are primarily used in hospitals and short-term care settings because they are a reactive method used to manage hyperglycemia in patients with fluctuating insulin requirements. This method addresses short-term blood sugar spikes on an immediate level – using surrounding meal times – rather than providing long-term consistent basal coverage.

How Does A Humalog Sliding Scale Work?

Patients using the Humalog sliding scale will have their blood sugar levels checked before their meals (or at set intervals). Those with higher blood sugar levels will need to take more corrective insulin. The exact amount of insulin they will have to take will be predetermined on the chart that is individualized to them – which has been prescribed by their healthcare provider – and corresponds to the exact blood sugar level they have at the time. For example (using the sample chart above in the “Humalog Sliding Scale Sample” section), a patient whose blood sugar level reads between 175 and 199 may be given 4 units of insulin.

Example of a Humalog Sliding Scale

A Humalog sliding scale chart is designed so that higher blood sugar readings correspond to higher corrective insulin doses. The goal is to bring high glucose levels back into a safer target range before meals or at scheduled monitoring times. Higher blood sugar levels correspond with higher doses that patients need to take to adjust their levels. For example, a provider may prescribe a sliding scale similar to:

Blood Sugar LevelAdministration Amount (in Units)
Under 700 (start hypoglycemia protocol)
Between 70 and 1500
Between 151 and 1742
Between 175 and 1994
Between 200 and 2246
Between 225 and 2498
Between 250 and 27410
Between 275 and 29912
Above 30014 (and call healthcare provider)


The numbers on the right side are the ranges where patients should identify where their current blood sugar level reading falls into. This number depends on the patient’s blood sugar readings, not just at fixed times. The corresponding number on the left side of the chart is the number of units of insulin that should be taken to adjust these levels. For example, a patient with a blood sugar reading of 190 would take 4 units of insulin to adjust their levels.

The exact numbers that would be in a patient’s prescribed sliding scale are not universal and may vary since it is prescribed individually. Providers adjust these charts to match individual insulin sensitivity and the clinical needs of the patient. It may also be adjusted based on factors such as the patient’s weight or other issues such as renal function and other comorbidities. They are typically structured to follow recognized clinical standards and the latest American Diabetes Association guidelines. For example, some protocols may recommend 14 units for readings above 300 mg/dL – along with instructions to contact a healthcare provider. Patients using a sliding scale method must follow their prescriber’s specific instructions.

When Humalog Sliding Scale Is Used

The Humalog sliding scale is most commonly used in hospital and inpatient care settings. This type of treatment is commonly ordered for non‑critically ill inpatients to correct stress‑ or illness‑related hyperglycemia when insulin needs are rapidly changing and meal intake is unpredictable. It may also be used for glucose management during illness or corticosteroid use. Sliding scale insulin is generally only recommended for certain short-term cases within an inpatient setting. It may still be used occasionally in scenarios such as temporary outpatient cases while long-term insulin therapy adjustments are still being made. It is not generally recommended for use as a sole long-term strategy.

Pros and Cons of Using a Sliding Scale

There may be some benefits and some downsides to using sliding scales for treatment.

Pros

  • This method is less complicated than methods that require the factoring in of carbohydrate counts and insulin ratios
  • Each sliding scale is specifically customized to the needs of the patients that it is being used to treat
  • Sliding scales are easy to use and understand
  • This method provides quick responses to high blood sugar levels

Cons

  • These scales do not account for activity or stress
  • This method does not account for variable snacks
  • Carbohydrates will still need to be identified and estimated
  • This method is less effective for pre-meal high blood glucose coverage
  • Patients may be at higher risk of developing hyper- and hypoglycemia due to blood sugar swings (especially if there is improper dosing resulting from errors such as incorrect blood sugar readings)
  • This method is reactive and not preventative
  • Sliding scales are often less effective than basal-bolus or carb-counting approaches for long-term control.

Risks and Safety Considerations

Using sliding scale insulin alone for a prolonged period in hospitalized patients with high blood sugar is strongly discouraged based on findings in clinical studies. Sliding scale insulin is commonly used in hospital settings to manage high blood sugar. However, it has been linked to a high rate of medication errors and side effects – including both hypoglycemia and hyperglycemia. These errors may occur as a result of problems such as incorrect blood sugar readings. This is why it is extra important to keep up with regular blood sugar monitoring and only use the sliding scale under the supervision of a healthcare professional.

Patients should also be aware that the use of a sliding scale may not prevent DKA or severe hyperglycemia if they have insulin resistance. It may instead actually prolong these issues since this method is reactive and does not provide enough steady insulin.

Alternative Dosing Regimens to Sliding Scale Insulin Dosing

Some patients may be able to use alternative dosing regimens for their insulin dosing. This includes possible options such as:

  • Basal-Bolus Insulin Therapy
    This type of therapy is for patients taking long- or intermediate-acting basal insulin to help regulate their blood. The patient then takes a bolus insulin that is rapid-acting before meals for additional regulation. This option does require patient education and involvement – which may not be suitable for all.
  • Carbohydrate Counting with Mealtime Insulin
    This type of therapy calls for the calculation of an insulin‑to‑carbohydrate ratio to represent the amount of carbohydrates that is covered by a single unit of insulin. This method can be used to calculate the amount of insulin needed for bolus insulin therapy. Like basal-bolus insulin therapy, this option also may not be suitable for all patients because it requires patient education and involvement.
  • Correction-Factor Dosing
    A correction factor allows patients to subtract their goal glucose level from their current glucose level and then divide that number by the correction factor – the starting point to get to this correction dose which can be found by using equations such as the “1800 rule” for rapid-acting insulin – to get the corresponding correction insulin dose. This method does not use a fixed chart and factors in personalized sensitivity. This option also requires periodic reassessment of insulin sensitivity – especially for fluctuating needs.
  • Continuous Glucose Monitoring and Insulin Pump Therapy
    These methods use technology-based sensors to continuously monitor the patient’s glucose levels. Continuous monitoring transmits this data to give the patient real-time monitoring information. Insulin pumps provide a steady delivery of rapid-acting insulin beneath the skin throughout the day. These are often better long-term solutions than using a sliding scale and may provide better control.

FAQs

Is a Humalog sliding scale still recommended?

Sliding scale insulin is still used in certain clinical situations – most commonly in hospitals or short-term inpatient settings. However, many healthcare providers prefer alternatives like basal-bolus therapy for long-term diabetes management because they provide more consistent blood sugar control.

A healthcare provider may prescribe a sliding scale for temporary outpatient use in some more rare cases. This is not typically recommended as a long-term standalone strategy at home.

A sliding scale uses a fixed chart that assigns insulin doses to specific blood sugar ranges. Correction-factor dosing uses a personalized formula to calculate the exact amount of insulin needed based on how sensitive the patient is to insulin. Correction dosing is generally more individualized and precise.

Yes. Sliding scale insulin is reactive and based solely on current glucose readings. Too much administration could lead to an increased risk of hypoglycemia. Patients using this treatment should regularly monitor their blood sugar and use this method only with close medical supervision.

Sliding scale insulin alone is generally not recommended for long-term diabetes management. It does not provide consistent basal insulin coverage and may lead to greater blood sugar fluctuations over time.

The Bottom Line

Humalog sliding scale insulin is a type of structured insulin that is sometimes used to correct high blood sugar in patients. This solution is usually only used for short-term treatment and in specific situations. Those who are looking for a new insulin strategy should discuss the most appropriate options for them with their healthcare provider.

Patients can find more affordable diabetes medications online at Duty Free Meds – including Humalog.

Sources
American Diabetes Association Professional Practice Committee. (2021). 16. Diabetes Care in the Hospital: Standards of Medical Care in Diabetes - 2022. Diabetes Care. Retrieved from https://doi.org/10.2337/dc22-s016
Colunga-Lozano, L. E., Torres, F. J. G., Delgado-Figueroa, N., Gonzalez-Padilla, D. A., Hernandez, A. V., Roman, Y., & Cuello-García, C. A. (2018). Sliding scale insulin for non-critically ill hospitalised adults with diabetes mellitus. Cochrane Database of Systematic Reviews, 2018(11), CD011296. Retrieved from https://doi.org/10.1002/14651858.cd011296.pub2
Donihi, A. C. (2006). Use of a standardized protocol to decrease medication errors and adverse events related to sliding scale insulin. BMJ Quality & Safety, 15(2), 89–91. Retrieved from https://doi.org/10.1136/qshc.2005.014381
Ernstmeyer, K., & Christman, E. (n.d.). Table 19.2, [Sample Sliding-Scale Insulin Protocol. Instructions:...]. Nursing Skills. NCBI Bookshelf. Retrieved from https://www.ncbi.nlm.nih.gov/books/NBK593194/table/ch19specimencollect.T.sample_slidingscal/
Farnoly, K. (2025, July 25). Personalizing Insulin Therapy: Tailoring Your Diabetes Treatment for Optimal Glucose Control. DiabetesSisters. Retrieved from https://diabetessisters.org/resources/personalizing-insulin-therapy-tailoring-your-diabetes-treatment-for-optimal-glucose-control/
HUMALOG SLIDING SCALE INSULIN COVERAGE. (n.d.). Senior Care Consultant Group. Retrieved from http://www.sccg.biz/generalDocuments/HUMALOG%20SLIDING%20SCALE%20INSULIN%20COVERAGE.pdf
Sliding scale insulin. (n.d.). Type 1 Diabetes Explained. Retrieved from https://www.t1dexplained.org/resources/insulin/sliding-scale
Vellanki, P., Cardona, S., Galindo, R. J., Urrutia, M. A., Pasquel, F. J., Davis, G. M., Fayfman, M., Migdal, A., Peng, L., & Umpierrez, G. E. (2022, June 8). Efficacy and Safety of Intensive Versus Nonintensive Supplemental Insulin With a Basal-Bolus Insulin Regimen in Hospitalized Patients With Type 2 Diabetes: A Randomized Clinical Study. Diabetes Care, 45(10), 2217–2223. Retrieved from https://doi.org/10.2337/dc21-1606

Disclaimer: The information presented here is intended solely for educational purposes and should not be interpreted as medical advice, a diagnosis, or specific treatment recommendations. It does not imply endorsement of any particular medication or therapy. Health conditions and treatment responses can differ significantly between individuals; thus, this information is not a guarantee of safety, suitability, or effectiveness for anyone in particular. Always seek the guidance of a healthcare professional for personalized medical advice and consult them before making any health or treatment decisions.

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