Anti-Nausea Medication

Anti-nausea meds are taken to treat nausea and vomiting. Typically, anti-nausea medications do not treat the cause of nausea. Instead, they either block the pathways found in the brain’s nausea center from reacting to neurotransmitters like serotonin, acetylcholine, and dopamine or stop the vomiting reflex caused by issues such as morning sickness, medical treatments like anesthesia, etc.

Types of Anti-Nausea Medications

Antihistamines

Antihistamines block histamine (H1) receptors in the brain that cause motion-related nausea and vomiting. Patients dealing with nausea triggered by motion sickness and ear disorders such as Meniere’s disease use this medication to drive away the feeling of vomiting.

Anticholinergics

Also referred to as antimuscarinics, these anti-nausea meds treat nausea by blocking acetylcholine, a neurotransmitter that sends nausea signals from the ear to the brain.

Serotonin (5-HT3) Antagonists

Physicians mostly use serotonin (5-HT3) antagonists to prevent nausea during chemotherapy, surgery, or radiation therapy. These meds inhibit serotonin from acting on the 5-HT3 receptors, which typically trigger nausea and vomiting.

Dopamine Antagonist

Dopamine antagonists block dopamine receptors in the brain’s vomiting center and also speed up stomach emptying. They are mainly used to treat nausea caused by medications and other factors like radiation and chemotherapy.

Cannabinoids

Cannabinoids are synthetic compounds similar to THC from cannabis. They interact with cannabinoid receptors in the brain to reduce chemotherapy-induced nausea and vomiting.

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