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Disclaimer: Images are for illustration purposes only. Brand-name products may appear different due to their country of origin—for example, medications from Canada will display "PR" on the packaging as required by law. For generic medications, we cannot guarantee a specific manufacturer, so appearances may vary, but rest assured the medication, dosage, and active ingredients will be exactly as prescribed. Your trust is important to us, and we're committed to providing you with safe and effective medications.
Disclaimer: Actual packaging received in-person may differ from images shown due to manufacturer updates or batch variations. Images are shown here as a general reference.
Delivery Times
From Canada
4–7 business days
From UK
7–10 business days
From Mauritius
10–14 business days
Shipping & Tracking Information
- Your medication is dispensed and shipped by licensed pharmacy partners.
- Tracking is sent once your order ships.
- Timing may vary depending on destination and prescription approval.
Eliquis (Apixaban)
Brand name for: Apixaban
Disclaimer: Images are for illustration purposes only. Brand-name products may appear different due to their country of origin—for example, medications from Canada will display "PR" on the packaging as required by law. For generic medications, we cannot guarantee a specific manufacturer, so appearances may vary, but rest assured the medication, dosage, and active ingredients will be exactly as prescribed. Your trust is important to us, and we're committed to providing you with safe and effective medications.
USA Price:
$696.00
Our Price:
$18.33
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It is imperative to note that Duty Free Meds adheres strictly to regulations regarding the dispensing of medications. We do not ship any products without a valid and appropriately matched prescription from a licensed U.S. healthcare provider. Additionally, we reserve the right to refuse service if there are any indications that the prescription may have been fabricated or altered. Ensuring the integrity of the prescription process is essential for your safety and well-being.
Medically Reviewed By
Dr Abdul Razzaque Nohri
Pharm D, MBA, M.Phil & MSPH
Reviewed On:
July 2, 2026
Medication Overview
Eliquis (apixaban) is a popular brand-name oral blood thinner medication that is used for the prevention of issues such as blood clots and stroke in patients who have nonvalvular AFib, deep vein thrombosis, or pulmonary embolism. It is also used to lower the risk of developing DVT blood clots following hip or knee replacement procedures. This medication usually comes in an oral formulation that is to be taken twice per day.
Why Choose Eliquis
This medication is beneficial to several groups of patients.
- This medication is given in an easy-to-use oral formulation
- Eliquis has uses for both adult and pediatric patients
- This blood-thinner medication can be used for treatment in patients with nonvalvular AFib, deep vein thrombosis, or pulmonary embolism
- Eliquis is also known to lower the risk of developing DVT blood clots following hip or knee replacement procedures
- This medication may help protect against stroke and systemic embolism in adults living with nonvalvular atrial fibrillation
Eliquis (Apixaban) Drug Facts
| Brand Name | Eliquis |
| Generic Name | Apixaban |
| Drug Class | Factor Xa inhibitor |
| Indication |
|
| Mechanism of Action | Prevents clot formation by targeting factor Xa and reducing thrombin generation |
| Dosage Forms | Oral tablets |
| Strengths | 2.5 mg or 5 mg (standard strengths) Note: 0.15 mg strength formulations may be available for the treatment of some pediatric patients |
| Half-life | 8-15 hours (usually about 12 hours) |
| Manufacturer | Bristol Myers Squibb |
Eliquis Dosage Guide
The dosage of Eliquis depends on the indication and the specific patient.
Adults with Nonvalvular Atrial Fibrillation (AFib)
The standard Eliquis dosage for most adults with nonvalvular atrial fibrillation is 5 mg taken twice each day. Some patients may require a reduced dose of 2.5 mg twice daily if they meet at least two of the following criteria:
- Are 80 years of age or older
- Weigh 60 kg (132 lbs) or less
- Have impaired kidney function (indicated by a serum creatinine level of 1.5 mg/dL or greater)
Prevention of Blood Clots After Hip or Knee Replacement Surgery
To help reduce the risk of blood clots following hip or knee replacement surgery, treatment is typically started with 2.5 mg taken twice daily beginning 12 to 24 hours after the procedure. Therapy is generally continued for 35 days after hip replacement surgery or 12 days after knee replacement surgery.
Treatment of DVT or PE
Patients using this medication for this treatment usually take 10 mg twice daily for the first seven days. They usually then continue with 5 mg twice daily following this.
Prevention of Returning DVT or PE
The recommended dose is 2.5 mg twice daily after completing at least six months of treatment.
Pediatric Patients
Dosing is based on the child’s weight and is started after at least five days of initial anticoagulant treatment. The healthcare provider will determine the appropriate dose and treatment duration.
Eliquis is not recommended to be taken by children weighing less than 2.6 kg (or 5.7 lbs). Patients using this medication should take it exactly as they are instructed to do so by their healthcare provider. Doses of this medication are usually taken twice per day with 12 hours between each dose. It does not matter whether or not this medication is taken on an empty or full stomach.
Missed doses of Eliquis should be taken as soon as they are remembered – as long as it is on the same day. However, doses should never be doubled to make up for any doses that were missed. Patients should skip their missed dose if it has been more than six hours since the time it was originally supposed to be taken. Patients who overdose on this medication should immediately call their local poison control center or emergency medical services.
Precautions & Warnings
Black Box Warnings
Eliquis has two different black box warnings assigned to it by the FDA. The first warning is about premature discontinuation of the medication. Prematurely stopping this medication – or other oral anticoagulants – can increase the patient’s risk of experiencing thrombotic events. Patients who need to stop Eliquis should talk to their doctor first and will likely be switched to another anticoagulant to reduce this risk if the medication is being stopped for a reason other than pathological bleeding or the end of treatment.
The second boxed warning for this medication is that an epidural or spinal hematoma can sometimes occur in patients using this medication who are also taking neuraxial anesthesia or who are undergoing spinal puncture. The development of these issues can cause serious long-term paralysis.
Other Warnings and Contraindications
Eliquis can also increase the risk of serious or life-threatening bleeding. Patients should contact a healthcare provider right away if they experience unusual bleeding, bruising, or signs of blood loss. A reversal agent is available in emergency situations to help counteract Eliquis’s blood-thinning effects. Eliquis is also generally not recommended for people with artificial or prosthetic heart valves.
This medication may cause an increased risk of blood clots in patients with triple-positive antiphospholipid syndrome and is also not recommended for patients in this group. Patients should also not use Eliquis if they are currently experiencing any abnormal bleeding or have an allergy to any of the ingredients of the medication. Advise a doctor of all medications and conditions in personal or family medical history before taking the medication.
Patients should not take Eliquis if they have active pathological bleeding or a serious hypersensitivity reaction to the medication or any of its contents. Signs of allergic reactions include those such as swelling or rash, troubles breathing, and other severe symptoms that indicate the need for immediate medical attention.
There are still no significant studies completed that focus on how this medication impacts pregnant women. Patients using this medication while pregnant or breastfeeding should weigh their benefits versus the potential risks before deciding to take this medication at the same time as pregnancy or breastfeeding.
Side Effects of Eliquis (Apixaban)
Apixaban affects blood clotting and can make bleeding more likely. Common signs may include:
- Cuts that take longer than normal to stop bleeding
- Frequent or prolonged nosebleeds
- Bleeding gums (particularly when brushing or flossing teeth)
- Bruises that appear easily or take longer than usual to heal
- Menstrual bleeding that is heavier or lasts longer than expected
The most common side effects for children include those such as heavier menstrual bleeding, headache, or vomiting. Additional side effects that some people may experience include:
- Nausea/upset stomach
- Skin irritation/rash
- Anemia (low red blood cell levels)
Many of the common side effects may resolve on their own over time and can be more common when doses are started or increased. Let a doctor know if any of these effects worsen, are severe, or do not go away on their own.
Serious Side Effects
Patients may experience more severe side effects in rare instances while taking Elquis. This may include effects such as increased risk of blood clots after stopping treatment. Stopping Eliquis without medical guidance can increase the risk of developing dangerous blood clots. These clots may lead to a stroke or other serious complications. Do not discontinue the medication without talking to a healthcare provider first.
Eliquis can also sometimes cause severe or life-threatening bleeding. Eliquis reduces the blood’s ability to clot and can cause serious bleeding that may require emergency medical attention. Seek immediate care if any of the following symptoms are experienced:
- Bleeding that is severe or difficult to stop
- Frequent nosebleeds or unusual gum bleeding
- Excessive bruising
- Heavier-than-normal menstrual bleeding
- Red, pink, or brown urine
- Black, tar-like, or bloody stools
- Coughing up blood or blood clots
- Vomiting blood or material that resembles coffee grounds
- Unexplained pain, swelling, or joint discomfort
- Severe headache, dizziness/fainting, or weakness
Eliquis may also cause serious spinal or epidural blood clots (hematomas) in rare cases. People who receive spinal injections, epidural anesthesia, or spinal punctures while taking Eliquis may develop a blood clot around the spinal cord. This can lead to the patient experiencing permanent nerve damage or paralysis. Patients should get immediate medical attention if they develop:
- Back pain
- Numbness or tingling in the legs or feet
- Muscle weakness
- Loss of bladder or bowel control
Seek immediate medical attention if any serious side effects are experienced.
Drug Interactions:
Eliquis increases the patient’s bleeding risk. This is why patients need to talk to their provider before combining this medication with the use of:
- Medications used to prevent or treat blood clots
- Clopidogrel
- Aspirin and products that contain aspirin
- Selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs)
- Any medication containing heparin
- Warfarin sodium
- Long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs)
- Other anticoagulant or antiplatelet medications
A provider’s review will determine whether or not these medications should be used together. Let a doctor know any medications or supplements being taken before starting the medication.
Storing and Handling Eliquis
Eliquis should be kept in a safe place with temperatures between 68°F and 77°F or 20°C and 25°C (room temperature). This medication may be used until the expiration date listed on the medication as long as it is kept in these safe storage conditions. This medication will be carefully packaged when shipped to patients’ homes in the U.S. to make sure these conditions are maintained.
Alternatives: to Eliquis
| Medication | Type | Indication | Manufacturer | Half-life | Onset Time | Available Strengths | Administration |
|---|---|---|---|---|---|---|---|
| Eliquis | Factor Xa inhibitor |
| Bristol Myers Squibb | Approximately 8-15 hours (average ~12 hours) | About 1-3 hours |
| Oral tablet |
| Pradaxa | Direct thrombin inhibitor |
| Boehringer Ingelheim | About 12 to 17 hours in healthy adult patients | About 1-3 hours |
| Oral capsule or oral pellets |
| Xarelto | Factor Xa inhibitor |
| Janssen Pharmaceuticals | About 5 to 9 hours in healthy adult patients | Rapid (almost immediately after administration) |
| Oral tablet or suspension |
Frequently Asked Questions (FAQ)
Do I need a prescription for Eliquis (Apixaban)?
Yes. Eliquis is a prescription-only medication in both the U.S. and Canada. Patients must have a valid prescription given to them by a licensed healthcare provider before they can purchase or receive Eliquis.
Can my Eliquis order be shipped from Canada to the US?
Yes, when ordering from Duty Free Meds, Eliquis can be shipped from Canada to the U.S. with a valid prescription.
Is there a generic for Eliquis?
Generic versions of Eliquis are approved but not available for sale in the US. Generic Eliquis, is however, available for sale in Canada. US patients can order generic Eliquis with US shipping at Duty Free Meds.
How much does Eliquis cost monthly?
The monthly cost of Eliquis can vary depending on the prescribed dose, quantity, and coverage. There are also differences between each pharmacy’s pricing. Patients paying out of pocket may find that prices differ significantly between pharmacies and countries – including Canada and the U.S.
How quickly does Eliquis thin your blood?
Eliquis begins working shortly after it is taken – with blood levels typically reaching their peak within about 3-4 hours. Eliquis can start helping prevent new blood clots from forming on the first day of treatment since it is a rapid-onset medication.
What should patients avoid during Eliquis treatment?
Patients taking Eliquis should avoid activities that increase the risk of injury or bleeding whenever possible. They should also speak with their healthcare provider before using medications such as aspirin, NSAIDs, or other blood thinners since these products can increase the risk of serious bleeding.
What are the downsides of Eliquis?
The most significant risk associated with Eliquis is bleeding – which can occasionally be serious or life-threatening. Some patients may also experience bruising more easily, prolonged bleeding from cuts, or increased bleeding during dental procedures and surgeries. Patients should discuss the potential risks and benefits with their healthcare provider prior to starting their treatment.
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Our Guarantee For Buying Eliquis From A Canadian Pharmacy Partner
Duty Free Meds is dedicated to providing reliable, top-quality medications with safety as our highest priority. We strictly adhere to the regulatory standards of each country we operate in, partnering exclusively with licensed Canadian pharmacies or vetted international providers to fulfill your order. Every product we offer is fully authorized by Health Canada or other respected organizations, including the MHRA in the United Kingdom, HSA in Singapore, and the Pharmacy Board of Mauritius. The medications are identical in composition to those available in the U.S., differing only in packaging that reflects their country of origin. We sell only genuine, authorized medications, and every order is thoroughly reviewed by our licensed healthcare team to ensure it matches your prescription precisely. To secure Eliquis at a reduced price, simply place your order above or call us at +1 888-234-2007.
Disclaimer: The information presented here is intended solely for educational purposes and should not be interpreted as medical advice, a diagnosis, or specific treatment recommendations. It does not imply endorsement of any particular medication or therapy. Health conditions and treatment responses can differ significantly between individuals; thus, this information is not a guarantee of safety, suitability, or effectiveness for anyone in particular. Always seek the guidance of a healthcare professional for personalized medical advice and consult them before making any health or treatment decisions.
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