Generic Semaglutide: Lower-Cost Semaglutide is Here!
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Generic Semaglutide: Lower-Cost Semaglutide is Here!
We Ship To The U.S. Only
Disclaimer: Images are for illustration purposes only. Brand-name products may appear different due to their country of origin—for example, medications from Canada will display "PR" on the packaging as required by law. For generic medications, we cannot guarantee a specific manufacturer, so appearances may vary, but rest assured the medication, dosage, and active ingredients will be exactly as prescribed. Your trust is important to us, and we're committed to providing you with safe and effective medications.
Delivery Times
From Canada
4–7 business days
From UK
7–10 business days
From Mauritius
10–14 business days
Shipping & Tracking Information
- Your medication is dispensed and shipped by licensed pharmacy partners.
- Tracking is sent once your order ships.
- Timing may vary depending on destination and prescription approval.
Trulicity Pen (Dulaglutide)
Disclaimer: Images are for illustration purposes only. Brand-name products may appear different due to their country of origin—for example, medications from Canada will display "PR" on the packaging as required by law. For generic medications, we cannot guarantee a specific manufacturer, so appearances may vary, but rest assured the medication, dosage, and active ingredients will be exactly as prescribed. Your trust is important to us, and we're committed to providing you with safe and effective medications.
USA Price:
$1,299.00
Our Price:
$294.99
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It is imperative to note that Duty Free Meds adheres strictly to regulations regarding the dispensing of medications. We do not ship any products without a valid and appropriately matched prescription from a licensed U.S. healthcare provider. Additionally, we reserve the right to refuse service if there are any indications that the prescription may have been fabricated or altered. Ensuring the integrity of the prescription process is essential for your safety and well-being.
Medically Reviewed By
Dr Abdul Razzaque Nohri
Pharm D, MBA, M.Phil & MSPH
Reviewed On:
August 26, 2026
Medication Overview
Trulicity (dulaglutide) is a prescription injectable medication that is used for improving glycemic control in adults and children aged 10 years and older with type 2 diabetes. Trulicity is intended to be used alongside a balanced diet and consistent physical activity as part of a treatment plan for managing blood glucose. Healthcare providers may also use the medication as part of an approach to cardiovascular risk reduction in adults living with type 2 diabetes – specifically when a patient has a history of cardiovascular disease or is considered at elevated risk for developing cardiovascular complications.
Why Choose Trulicity?
Trulicity patients can experience many benefits from taking the medication. These may include benefits such as:
- Lowered A1C levels (when combined with proper diet and exercise)
- A once-per-week dosing schedule
- May help with major cardiovascular events risk reduction in adults with type 2 diabetes who have established heart disease or other factors that increase cardiovascular risk
- Availability for use in some pediatric patients with type 2 diabetes (aged at least 10 years old)
- Possible weight loss (this is a secondary effect and not an indicated use for this medication)
Trulicity Drug Facts
| Brand Name | Trulicity |
| Generic Name | Dulaglutide |
| Drug Class | GLP-1 receptor agonist |
| Indication |
|
| Mechanism of Action | Mimics natural GLP-1 for increased insulin secretion, slows gastric emptying, and reduces glucagon secretion |
| Dosage Forms | Single-dose injection pens |
| Strengths |
|
| Half-life | About 5 days |
| Manufacturer | Eli Lilly and Company |
Trulicity Dosage Directions
Adult patients on this medication are generally prescribed a starting dose of 0.75 mg for at least the first four weeks of using the medication. Adult patients may then have their dose increased to 1.5 mg per week to give them additional glycemic control. This dose may then be increased to 3 mg per week after at least four more weeks of use if a doctor determines additional glycemic control is needed. The maximum dose that can be prescribed is 4.5 mg per week. Patients will have to be on the 3 mg per week dose for at least four weeks before this dose can be prescribed. Pediatric patients are usually given the same 0.75 mg starting dose. However, the maximum dose they are usually prescribed is 1.5 mg if necessary (after a minimum of the first four weeks on the medication).
How to Use Trulicity Pens
Trulicity comes in the form of single-use injection pens. Patients can give themselves their weekly medication using these pens by:
- Removing the pen from the refrigerator (do not take the base cap off yet)
- Checking the label on the pen to make sure it is not expired and the correct medication is being used
- Inspect the pen to make sure it is not damaged, and the medication is still free of color, cloudiness, and particles
- Thoroughly wash hands
- Identify and locate the injection site recommended by the healthcare provider in the thigh, upper arm, or abdomen (this site should be changed with each injection that is made)
- Pull off the base cap from the pen and dispose of it in the household trash without touching the needle
- Place the clear base flat against the location the injection is going to be made
- Unlock the pen by turning the lock ring
- Locate the green injection button and press and hold it (a loud click sound should be heard)
- Continue to press down this button until a second click is heard (this generally takes somewhere between five and 10 seconds)
- Remove the pen from the skin (the gray plunger should be visible once the injection is complete)
- Dispose of the pen in an FDA-cleared sharps container immediately after use
Patients using this medication with insulin must make sure that both injections are separated – never mixed – and injections in the same body region should not be adjacent. Those who accidentally miss doses of their medication should take the missed dose only when at least 72 hours remain before the next scheduled dose – otherwise the missed dose should be skipped.
Precautions & Warnings
Black Box Warning
Dulaglutide caused dose- and treatment-duration-dependent thyroid C-cell tumors in rats in rodent studies and has indicated the potential of medications like Trulicity causing these tumors (including medullary thyroid carcinoma) in humans. It is still unknown what this study means for use in humans. However, this is the reason that the medication has a black box warning and is not to be used in patients with histories – family or personal – of MTC. The same goes for patients with personal histories of Multiple Endocrine Neoplasia syndrome type 2.
Other Warnings and Contraindications
Patients should be extra cautious about using Trulicity with insulin secretagogues or insulin since this may increase their risk of developing hypoglycemia. This can be severe and reducing the dose of either the insulin or an insulin secretagogue – such as a sulfonylurea – may be necessary. may be necessary before starting Trulicity. Rare but serious hypersensitivity reactions may occur in some patients. This requires immediate medical attention and the medication should be avoided by patients with known reactions to the medication or any of its ingredients.
Patients on this medication may experience severe gastrointestinal reactions in some cases. Patients with severe gastroparesis should generally avoid the use of Trulicity. Some of Trulicity’s side effects may lead to volume depletion. Patients experiencing these effects should have their renal function monitored as it could lead to acute kidney injury.
Patients with a history of diabetic retinopathy should be monitored while using this medication as there have been reported instances of diabetic retinopathy complications in cardiovascular outcomes trials. Patients with pre-existing diabetic retinopathy require monitoring for progression. Gallbladder studies are to be done on patients if they are suspected to have cholelithiasis or cholecystitis as this medication can also lead to acute gallbladder disease in some rare instances.
Some surgeries and procedures using general anesthesia or deep sedation can lead to pulmonary aspiration during use of this medication. There have been rare postmarketing reports of pulmonary aspiration and available evidence is insufficient to determine whether fasting changes or temporary drug discontinuation reduce that risk. It is important for healthcare providers to be made aware of any surgeries or procedures ahead of time while using Trulicity.
Current labeling states that human pregnancy data are limited. Animal data indicate potential fetal risk and there are no human data on dulaglutide in breast milk or effects on the breastfed infant. Always let a doctor know before using this medication while pregnant or breastfeeding. Patients should also let a doctor know of any medications or supplements being taken while on this medication.
Side Effects of Trulicity
The side effects that are most often reported by those on Trulicity are those such as:
- Fatigue
- Indigestion
- Decrease in appetite
- Abdominal pain or nausea
- Vomiting or diarrhea
Not everyone may experience one of the above effects. However, it is important to know them. Patients should talk to their doctor right away if they are experiencing any worsening or persistent side effects.
Serious Side Effects
Serious side effects may also occur on some occasions. This may include effects such as:
- Pancreatitis (stop use and seek medical care for persistent severe abdominal pain, with or without nausea/vomiting, that may radiate to the back)
- Hypoglycemia (risk is increased when used with insulin or sulfonylureas)
- Dehydration/kidney problems (usually due to volume depletion from side effects of the medication)
- Severe gastrointestinal problems
- Diabetic retinopathy (these complications were found in trials and patients with pre-existing diabetic retinopathy require monitoring for progression)
- Gallbladder problems (seek medical attention for upper abdominal pain, fever, jaundice, or clay-colored stools)
- Aspiration from anesthesia (inform healthcare providers before surgery or procedures requiring anesthesia or deep sedation)
- Serious allergic reactions (seek emergency medical attention for facial swelling, difficulty breathing/swallowing or fainting, rash, or rapid heartbeat)
Patients experiencing any of the above side effects should seek immediate medical attention.
Drug Interactions:
Trulicity may interact with some oral medications by delaying gastric emptying which can potentially change the rate at which these medications are absorbed. Concomitant use with insulin or sulfonylureas may also increase the risk of hypoglycemia. The patient’s doctor may consider reducing the dose of insulin or insulin secretagogues when initiating Trulicity if it is being used to reduce this risk. Current labeling also recommends monitoring drug levels for oral medicines with a narrow therapeutic index – such as warfarin – when administered with Trulicity. Always talk with a healthcare provider to get personal advice before combining medications.
How To Store Trulicity Pens
Trulicity pens are to be stored in the refrigerator at temperatures between 36°F and 46°F (2°C and 8°C) and never frozen. These pens can also be stored at room temperature – as long as it does not exceed 86°F (30°C) – for up to 14 days. The medication should be disposed of if it exceeds this temperature, is left out for more than 14 days, or becomes frozen. The medication should also be stored in its original container and be protected from light until use. These medications are carefully packed with cold packs when shipped to the U.S.
Trulicity Alternatives:
| Medication | Type | Indication | Manufacturer | Duration in the body | Onset Time | Available Strengths | Administration |
|---|---|---|---|---|---|---|---|
| Trulicity | GLP‑1 receptor agonist | Type 2 diabetes | Eli Lilly and Company | About three to four weeks (based on the 5-day half-life) | Within days (or up to weeks for full effects) after administration |
| Prefilled disposable injection pen |
| Ozempic | GLP‑1 receptor agonist | Type 2 diabetes | Novo Nordisk | Up to five weeks before full elimination | Within days (or up to weeks) after administration |
| Prefilled disposable injection pen |
| Rybelsus | GLP‑1 receptor agonist | Type 2 diabetes | Novo Nordisk | About 5 weeks | Within days to weeks of regular use |
| Oral tablet |
Frequently Asked Questions
Do I need a prescription for Trulicity?
Yes. Trulicity is a prescription-only medication. A licensed healthcare provider must determine whether it is appropriate based on the patient’s needs and medical history and provide a prescription before the medication may be purchased.
Can I order Trulicity to the US?
Eligible patients may be able to order Trulicity from licensed international pharmacies or prescription fulfillment services, like Duty Free Meds, and have it shipped to their homes in the U.S. A valid prescription from a healthcare provider is required before the medication can be dispensed. However, importing prescription medicines from abroad is subject to U.S. federal law and FDA requirements. Personal importation is not a general right or guarantee. FDA may exercise enforcement discretion in certain circumstances based on factors such as the medication, the patient’s circumstances, and the quantity being imported. The medication must also be used for personal use only.
Is Trulicity considered to be a type of insulin medication?
No. Trulicity is not insulin. It belongs to a class of medications called GLP-1 receptor agonists and helps with insulin release, reduces glucagon secretion, and slows gastric emptying.
How do Trulicity and Ozempic differ?
Both are types of type 2 diabetes medications from the GLP-1 receptor agonist class. The main difference is that Trulicity contains dulaglutide. Semaglutide is the ingredient that is used in Ozempic – not dulaglutide.
How much should patients expect to pay for Trulicity without insurance?
The current list price of Trulicity is about $1,006 in the U.S. Patients may pay around this much if they are not using any coverage in the U.S. or they may find this medication for closer to $295 per month when they order from Canada. Exact prices vary by location, insurance coverage, and available savings programs.
Can Trulicity help with weight loss?
Some patients lose weight while taking Trulicity. However, weight loss is not one of this medication’s approved uses. Any weight reduction is considered a secondary effect of treatment for type 2 diabetes and may vary from person to person.
Do I need to refrigerate my Trulicity pen?
Trulicity pens should be stored in the refrigerator between 36°F and 46°F (2°C to 8°C). A pen may be kept at room temperature below 86°F (30°C) for up to 14 days before it should be discarded if needed.
Is Ozempic better than Trulicity?
Neither medication is considered universally better. Both are effective GLP-1 receptor agonists for managing type 2 diabetes but they differ in their active ingredients, dosing options, and clinical effects. Patients can determine the best option for them by talking with their healthcare provider.
How many doses does each Trulicity injection pen contain?
A single Trulicity pen provides one measured dose and is designed to be used for one administration. The pen should be disposed of in an FDA-cleared sharps container after the injection is complete.
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Our Guarantee For Buying Trulicity Pen From A Canadian Pharmacy Partner
Duty Free Meds is dedicated to providing reliable, top-quality medications with safety as our highest priority. We strictly adhere to the regulatory standards of each country we operate in, partnering exclusively with licensed Canadian pharmacies or vetted international providers to fulfill your order. Every product we offer is fully authorized by Health Canada or other respected organizations, including the MHRA in the United Kingdom, HSA in Singapore, and the Pharmacy Board of Mauritius. The medications are identical in composition to those available in the U.S., differing only in packaging that reflects their country of origin. We sell only genuine, authorized medications, and every order is thoroughly reviewed by our licensed healthcare team to ensure it matches your prescription precisely. To secure Trulicity Pen at a reduced price, simply place your order above or call us at +1 888-234-2007.
Disclaimer: The information presented here is intended solely for educational purposes and should not be interpreted as medical advice, a diagnosis, or specific treatment recommendations. It does not imply endorsement of any particular medication or therapy. Health conditions and treatment responses can differ significantly between individuals; thus, this information is not a guarantee of safety, suitability, or effectiveness for anyone in particular. Always seek the guidance of a healthcare professional for personalized medical advice and consult them before making any health or treatment decisions.
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